Factory Supply Pharmaceutical Synthetic Anti-Infective Drugs Tmp Trimethoprim Powder CAS 738-70-5 Trimethoprim
| Product Name |
Factory Supply Pharmaceutical Synthetic Anti-Infective Drugs Tmp Trimethoprim Powder CAS 738-70-5 Trimethoprim |
| Appearance |
White powder |
| Molecular formula |
C14H18N4O3 |
| Molecular Weight |
290.32 |
| Keywords |
Tmp Trimethoprim;Trimethoprim Powder;Purity Trimethoprim |
| Shelf Life |
24 months when properly stored |
| Storage |
Keep in a cool, dry, dark location |
 |
What is Trimethoprim ?
Trimethoprim is a bacteriostatic antibiotic used mainly in the prophylaxis and treatment of urinary tract infections.Target: DHFRTrimethoprim (TMP), an inhibitor of dihydrofolate reductase, decreases the level of tetrahydrofolate supplying one-carbon units for biosynthesis of nucleotides, proteins, and panthotenate. . |
Function of Trimethoprim
TMP caused induction of DnaK, DnaJ, GroEL, ClpB, and IbpA/B Hsps. Among these Hsps, IbpA/B were most efficiently induced by TMP and coaggregated with the insoluble proteins [1]. Trimethoprim binds to dihydrofolate reductase and inhibits the reduction of dihydrofolic acid (DHF) to tetrahydrofolic acid (THF). THF is an essential precursor in the thymidine synthesis pathway and interference with this pathway inhibits bacterial DNA synthesis. .
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Application of Trimethoprim
Trimethoprim's affinity for bacterial dihydrofolate reductase is several thousand times greater than its affinity for human dihydrofolate reductase. Sulfamethoxazole inhibits dihydropteroate synthetase, an enzyme involved further upstream in the same pathway. Trimethoprim and sulfamethoxazole are commonly used in combination due to their synergistic effects. This drug combination also reduces the development of resistance that is seen when either drug is used alone..
Veterinary Medicine Raw Material Tmp powder CAS 738-70-5 Trimethoprim
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Xi'an International Healthcare Factory Co., Ltd., was established in May 2010,and located in Gaoling Industrial
Park, Xi'an city, Shaanxi Province, China. It is a professional supplier of veterinary medicine, pharmaceutical ,raw material
,Vertinary drug ,medicine,Plant Extractand natural active ingredients It has absolute advantage because of strong
research strength, modern management system and high-quality marketing team.
Now we have 3 GMP standard workshop, Meanwhile, the factory is equipped with the researching and quality inspection
centre, with strong technology research and development strength. We also have 3 sales departments over 30 people and
sell our products all over the world.
For customer's needs, OEM service is also acceptable. If you have a good idea in new product production but lack of
laboratory device and human resource, we are glad to solve this problem for you. Sincerely hope to strengthen exchanges
and cooperation with friends from both home and abroad.
Q: What's your MOQ ?
A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.
Q: Is there a discount ?
A: Yes, for larger quantity, we always support with better price.
Q: How to confirm the Product Quality before placing orders ?
A: You can get free samples for some proucts, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.
Q: How to start orders or make payments ?
A: You can send our your Purchase order ( if your company has ), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.
Q: How do you treat quality complaint ?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.
Factory Supply Pharmaceutical Synthetic Anti-Infective Drugs Tmp Trimethoprim Powder CAS 738-70-5 Trimethoprim
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