Customization: | Available |
---|---|
CAS No.: | 152459-95-5 |
Formula: | C29h31n7o |
Still deciding? Get samples of US$ 30/gram
Request Sample
|
Suppliers with verified business licenses
Audited by an independent third-party inspection agency
Product Name | High Quality Organic Pharmaceutical Intermediate Anti-Cancer Raw Material Imatinib Powder CAS 152459-95-5 |
Shape | White powder |
Molecular formula | C29H31N7O |
Keywords | Imatinib Mesylate;Chemical Powder Imatinib;Anticancer Imatinib |
Shelf Life | 24 months when properly stored |
Storage | Keep in a cool, dry, dark location |
What is Imatinib ? Imatinib Mesylate is a specific tyrosine kinase (abl, c-kit, and PDGFR) inhibitor and is reported to sensitize cells to radio- or chemo-therapy. When tested with Y-79 and WERI-RB-1 Rb cell lines, imatinib mesylate treatment decreased the cell proliferation and invasion with the concentration of 10 μM . In osteoblast cells, administration of imatinib mesylate decreased osteoclast development via stimulating differentiation, inhibiting proliferation and survival . |
Cells were stimulated with allogeneic mature DCs or PHA in the presence of imatinib mesylate. The drug inhibited T-cell proliferation as a function of concentration. The effects were significant at 0.5 μM imatinib mesylate for the cells stimulated by DCs and at 1.0 μM imatinib mesylate for the cells stimulated with PHA. The IC50 values for imatinib mesylate-inhibited T-cell proliferation stimulated by DCs and PHA were 3.9 μM and 2.9 μM, respectively..
Q: What's your MOQ ?
A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.