CAS No.: | 27262-48-2 |
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Formula: | C18h29cln2o |
EINECS: | 1308068-626-2 |
Type: | Organic Intermediate |
Appearance: | Powder |
Quality: | Industrial |
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Product Name | Wholesale Anesthetic Raw Material 99% Levobupivacaine HCl/Hydrochloride Powder CAS 27262-48-2 Levobupivacaine |
Appearance | White powder |
Molecular formula | C18H29ClN2O |
Keywords | Anesthetic Levobupivacaine Hydrochloride;Levobupivacaine Hydrochloride;Levobupivacaine Hydrochloride Powder |
Shelf Life | 24 months when properly stored |
Storage | Keep in a cool, dry, dark location |
What is Levobupivacaine? Levobupivacaine is indicated for local anaesthesia including infiltration, nerve block, ophthalmic, epidural and intrathecal anaesthesia in adults; and infiltration analgesia in children. |
Levobupivacaine was first launched in the US for the production of local anesthesia for surgery and obstetrics and for post-operative pain management. It is the (S)-enantiomer of the long acting, highly potent local anesthetic bupivacaine (Marcaine) that can be prepared by a three step sequence from (S)-pipecolic acid or from (S)-lysine by oxidative deamination and stereospecific ring closure to (S)-pipecolamide core structure. Levobupivacaine exhibits its long-acting local anesthetic effect by blocking neuronal sodium channel ion flow in nerve axons. Clinical studies demonstrated an efficacy and a general profile closely resembling those of the racemic bupivacaine currently in use; however, it produced an enhanced safety profile, in particular substantially reduced (about one-third) cardiotoxicity (less effect on myocardial contractility and QT, prolongation) and CNS depressive side effects. Onset and duration of blockade were also equivalent or even better.
Q: What's your MOQ ?
A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.
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