Top Quality Pharmaceutical Chemicals 99% Raw Material Powder CAS 152044-54-7 Epothilone B
Product Name |
Top Quality Pharmaceutical Chemicals 99% Raw Material Powder CAS 152044-54-7 Epothilone B |
Appearance |
white powder |
CAS |
152044-54-7 |
Assay |
99% |
Keywords |
Raw Material Epothilone B;Epothilone B Powder;Pharmaceutical Chemicals Epothilone B |
Shelf Life |
24 months when properly stored |
Storage |
Keep in a cool, dry, dark location |
 |
What is Epothilone?
EpothiloneA was found in the celllosum of Myxobacteria Sorangiumcellulosum. It is a microtubule stabilizer similar to.which induces the polymerization of tubulin and leads to the cell cycle stopping at g2-M phase, which produces toxicity and also induces apoptosis. The EC0.01 value of EpothiloneA is 2μM. EpothiloneA effectively inhibited the proliferation of HCT116 cells with IC50 of 4.4nM. EpothiloneA acts on KB3-1,KBV-1,Hela, and Hs578T cells and has cytotoxic Chemicalbook with IC50 ranging from 13nM to 160nM. EpothiloneA is more water-soluble than and it competitively binds to microtubules with IC50 of 2.3μM. However,EpothiloneA and Taxol do not share a pharmacophore, and they independently and specifically utilize their tubulin binding bags. The newly discovered Transformation of EpothiloneA caused by AspergillusnigerAS3.739 produced metabolites that were toxic to McF-7 cells but had very high IC50 values. |
Function of Epothilone
Epothilone, a class of macrolides, was first reported by G. Hoffle et al., National Center for Biotechnology (GBF), Germany, in chemical Book 993. Ebomycin was isolated from the fermentation broth of the suborder Myxobacteria, cystis fibrinosa. The main components of ebomycin were EpothiloneA and B.
Application of Epothilone
GMP Raw Material Patupilone powder CAS 152044-54-7 Epothilone B
Pharmaceuticals GMP Raw Material Patupilone powder CAS 152044-54-7 Epothilone B
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Xi'an International Healthcare Factory Co., Ltd., was established in May 2010,and located in Gaoling Industrial
Park, Xi'an city, Shaanxi Province, China. It is a professional supplier of veterinary medicine, pharmaceutical ,raw material
,Vertinary drug ,medicine,Plant Extractand natural active ingredients It has absolute advantage because of strong
research strength, modern management system and high-quality marketing team.
Now we have 3 GMP standard workshop, Meanwhile, the factory is equipped with the researching and quality inspection
centre, with strong technology research and development strength. We also have 3 sales departments over 30 people and
sell our products all over the world.
For customer's needs, OEM service is also acceptable. If you have a good idea in new product production but lack of
laboratory device and human resource, we are glad to solve this problem for you. Sincerely hope to strengthen exchanges
and cooperation with friends from both home and abroad.
Pharmaceutical Raw Material Package;API Raw Material; Pharmaceutical Raw Materials; Pharma Raw Material Factory; Pharmaceutical Intermediate
Active Pharmaceutical Ingredients Raw Material; Pharmaceutical Active Ingredients, Pharmaceutical Intermediates, API Raw Material Supplier




Q: What's your MOQ ?
A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.
Q: Is there a discount ?
A: Yes, for larger quantity, we always support with better price.
Q: How to confirm the Product Quality before placing orders ?
A: You can get free samples for some proucts, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.
Q: How to start orders or make payments ?
A: You can send our your Purchase order ( if your company has ), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.
Q: How do you treat quality complaint ?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.
Top Quality Pharmaceutical Chemicals 99% Raw Material Powder CAS 152044-54-7 Epothilone B