Customization: | Available |
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Powder: | Yes |
Customized: | Customized |
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Product Name | High Quality Pharmaceutical Nepafenac Powder CAS 78281-72-8 Nepafenac Used for Anti-Inflammatory Drug |
Appearance | yellow powder |
CAS | 78281-72-8 |
Assay | 99% |
Keywords | Nepafenac;Nepafenac Powder;Nepafenac CAS 78281-72-8 |
Shelf Life | 24 months when properly stored |
Storage | Keep in a cool, dry, dark location |
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What is Nepafenac ? Nepafenac is a novel ocular non-steroidal antipyretic, analgesic and anti-inflammatory drug (NSAIDs). Nepafenac is used to treat eye pain and inflammation caused by cataract surgery. Compared with traditional NSAIDs, the chemical structure of Nepafenac is favorable for the drug to rapidly penetrate the cornea and distribute at its target site. Therefore, it is helpful to reduce the accumulation of drugs on the surface of the cornea, reduce the occurrence of complications on the surface of the eye, and has the advantages of strong penetration, strong targeting effect and small toxic and side effects. |
Nepafenamine, when administered via the eye, rapidly passes through the cornea and is converted to amifenic acid (an NSAID) by hydrolases in the eye tissue; Amifenic acid plays an anti-inflammatory and analgesic role by inhibiting prostaglandin H synthetase (cyclooxygenase) and blocking the synthesis of prostaglandin. As is well known, prostaglandins are mediators that cause inflammation in the eye, leading to breakdown of the blood-aqueous barrier, vasodilation, increased vascular permeability and leukocyte chemotactic, etc. In addition, prostaglandins can also contract the iris sphincter through non-cholinergic mechanisms, leading to the constriction of the eyes during and after ophthalmic surgery. When administered via the eye, NSAIDs inhibit the synthesis of prostaglandins in the iris, ciliary body, and conjunctiva, thereby preventing eye inflammation and reducing associated pain.
Q: What's your MOQ ?
A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.