Top Quality Organic Synthetic Intermediate Epothilone B Powder CAS 152044-54-7 Epothilone B

• CAS No.: 152044-54-7
• Formula: C27h41no6s
• EINECS: 604-822-6
• Type: Organic Intermediate
• Appearance: Powder
• Quality: Industrial
• Model NO.: IHF-Epothilone B
• Colour: White
• Product Name: Epothilone
• Certificate: GMP ISO USP Bp
• Assay: 99% Min
• Test: HPLC
• CAS: 152044-54-7
• Mf: C27h41no6s
• Active Ingredient: Epothilone
• Sample: Epothilone Avaliable
• Grade Standard: Medicine Grade
• Application: API Raw Materials
• Type of Product: Auxiliaries and Other Medicinal Chemicals
• Storage: Cool Dry Place
• Shelf Life: 2 Years Proper Storage
• Keywords: Epothilone Powder
• MOQ: 1kg
• Transport Package: 1kg Per Foil Bag, 10 Bags Per Carton. 25 Kg Per Dr
• Specification: 99% min
• Trademark: Inter-Health
• Origin: Shaanxi China
• Production Capacity: 500000kg/Year

Product Description

Top Quality Organic Synthetic Intermediate Epothilone B Powder CAS 152044-54-7 Epothilone B

Product Name	Top Quality Organic Synthetic Intermediate Epothilone B Powder CAS 152044-54-7 Epothilone B
Appearance	white powder
CAS	152044-54-7
Assay	99%
Keywords	Epothilone B;Epothilone B Powder;Epothilone B CAS 152044-54-7
Shelf Life	24 months when properly stored
Storage	Keep in a cool, dry, dark location

 

What is Epothilone? EpothiloneA was found in the celllosum of Myxobacteria Sorangiumcellulosum. It is a microtubule stabilizer similar to.which induces the polymerization of tubulin and leads to the cell cycle stopping at g2-M phase, which produces toxicity and also induces apoptosis. The EC0.01 value of EpothiloneA is 2μM. EpothiloneA effectively inhibited the proliferation of HCT116 cells with IC50 of 4.4nM. EpothiloneA acts on KB3-1,KBV-1,Hela, and Hs578T cells and has cytotoxic Chemicalbook with IC50 ranging from 13nM to 160nM. EpothiloneA is more water-soluble than  and it competitively binds to microtubules with IC50 of 2.3μM. However,EpothiloneA and Taxol do not share a pharmacophore, and they independently and specifically utilize their tubulin binding bags. The newly discovered Transformation of EpothiloneA caused by AspergillusnigerAS3.739 produced metabolites that were toxic to McF-7 cells but had very high IC50 values.

 
Function of Epothilone

Epothilone, a class of macrolides, was first reported by G. Hoffle et al., National Center for Biotechnology (GBF), Germany, in chemical Book 993. Ebomycin was isolated from the fermentation broth of the suborder Myxobacteria, cystis fibrinosa. The main components of ebomycin were EpothiloneA and B.

Application of Epothilone

GMP Raw Material Patupilone powder CAS 152044-54-7 Epothilone B

Pharmaceuticals GMP Raw Material Patupilone powder CAS 152044-54-7 Epothilone B

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Q: What's your MOQ ?

A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.

 

Q: Is there a discount ?

A: Yes, for larger quantity, we always support with better price.

 

Q: How to confirm the Product Quality before placing orders ?

A: You can get free samples for some proucts, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.

 

Q: How to start orders or make payments ?

A: You can send our your Purchase order ( if your company has ), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.

 

Q: How do you treat quality complaint ?

A: First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.