Pharmaceutical APIs Irinotecan CAS 100286-90-6 Irinotecan Hydrochloride powder
Product Name |
Pharmaceutical APIs Irinotecan CAS 100286-90-6 Irinotecan Hydrochloride powder |
Appearance |
White powder |
Molecular formula |
C33h39cln4o6 |
Keywords |
Gemcitabine hydrochlorid,Granisetron hydrochloride powder,107007-99-8 Granisetron hydrochloride |
Shelf Life |
24 months when properly stored |
Storage |
Keep in a cool, dry, dark location |
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What is Irinotecan hydrochloride
lrinotecan hydrochloride, a semi-synthetic, water soluble derivative of the potent anticancer agent camptothecin, was launched in Japan for the treatment of lung, ovarian, and cervical cancers. lrinotecan exerts its antitumor activity via inhibition of topoisomerase I, a cellular enzyme that is involved in maintaining the topographic structure of DNA during the process of translation, transcription, and mitosis.
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Function of Irinotecan hydrochloride
lrinotecan undergoes de-esterification in vivo to yield an active metabolite, SN-38, which is 1000-fold more potent than the parent. Although being much less toxic than camptothecin, a significant number of patients in clinical trials exhibited side effects of leukopenia, diarrhea, nauseahromiting, and alopecia. Combination therapy of irinotecan with another widely used anticancer agent, cisplatin, has been reported to be superior to either agent alone. lrinotecan is in clinical trials for gastrointestinal, breast, skin, colorectal, pancreatic cancers, mesothelioma and non-Hodgkin's lymphoma.
Application of Irinotecan hydrochloride
antineoplactic;A DNA topoisomerase inhibitor
Pharmaceutical APIs Irinotecan CAS 100286-90-6 Irinotecan Hydrochloride powder
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Q: What's your MOQ ?
A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.
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A: Yes, for larger quantity, we always support with better price.
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