High Purity Pharmaceutical Intermediate Raw Material Fasudil Powder CAS 103745-39-7 Fasudil
| Product Name |
High Purity Pharmaceutical Intermediate Raw Material Fasudil Powder CAS 103745-39-7 Fasudil |
| Appearance |
White powder |
| Molecular formula |
C14H18ClN3O2S |
| Molecular Weight |
327.83 |
| Keywords |
Powder Fasudil;Raw Material Fasudil;Pharmaceutical Intermediate Fasudil |
| Shelf Life |
24 months when properly stored |
| Storage |
Keep in a cool, dry, dark location |
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What is Fasudil ?
Fasudil hydrochloride, a novel calcium antagonistic vasodilator, was marketed for the treatment of cerebral vasospasm following subarachnoid hemorrhage (SAH). Fasudil is also a potent inhibitor of myosin light chain kinase and protein kinase C. In contrast to other calcium channel blockers, which regulate the influx of calcium ions through the cell membrane but not involved in the intracellular regulatory mechanism of the calcium, fasudil was suggested to have an intracellular mode of action in relaxing vascular smooth muscle. In patients with neurological deficits due to vasospasm, fasudil decreased the occurrence of angiographic severe and symptomatic vasospasm and cerebral infarction without decreasing systemic blood pressure. Fasudil is reportedly in clinical trials for acute ischemic stroke, sequelae of cerebral vascular diseases and angina pectoris....
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Function of Fasudil
Fasudil hydrochloride is a new drug with a wide range of pharmacological effects. It was first developed by Asahi Kasei in Japan and first marketed in Japan in June 1995. In 2001, China approved Japan Asahi Kasei Corporation to import Fasudil hydrochloride injection under the trade name of "Irilu". Its molecular structure is 5-isoquinoline sulfonamide derivative, which is a RHO kinase inhibitor. By increasing the activity of myosin light chain phosphatase, it dilates blood vessels, reduces the tension of endothelial cells, improves the microcirculation of brain tissue, does not produce or aggravate brain blood theft, and can antagonize inflammatory factors, protect nerve against apoptosis and promote nerve regeneration.
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Application of Fasudil
Fasudil hydrochloride can promote the recovery of nervous function, relieve clinical symptoms and reduce the rate of disability. Therefore, the ultra-early thrombolytic therapy cannot be realized at the primary level due to the restriction of economic conditions and the degree of understanding of the disease. However, in order to reduce the further progress of the disease, it is very important to rebuild the local blood circulation within the treatment time window. Fasudil hydrochloride has significant neuroprotective and therapeutic effects on ischemic cerebrovascular disease, which is worthy of clinical use, especially at the primary level. Reduce disability rates and improve quality of life.
Pharmaceutical Raw Materials Fasudil HCl CAS 105628-07-7 Fasudil Hydrochloride Powder
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Xi'an International Healthcare Factory Co., Ltd., was established in May 2010,and located in Gaoling Industrial
Park, Xi'an city, Shaanxi Province, China. It is a professional supplier of veterinary medicine, pharmaceutical ,raw material
,Vertinary drug ,medicine,Plant Extractand natural active ingredients It has absolute advantage because of strong
research strength, modern management system and high-quality marketing team.
Now we have 3 GMP standard workshop, Meanwhile, the factory is equipped with the researching and quality inspection
centre, with strong technology research and development strength. We also have 3 sales departments over 30 people and
sell our products all over the world.
For customer's needs, OEM service is also acceptable. If you have a good idea in new product production but lack of
laboratory device and human resource, we are glad to solve this problem for you. Sincerely hope to strengthen exchanges
and cooperation with friends from both home and abroad.
Q: What's your MOQ ?
A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.
Q: Is there a discount ?
A: Yes, for larger quantity, we always support with better price.
Q: How to confirm the Product Quality before placing orders ?
A: You can get free samples for some proucts, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.
Q: How to start orders or make payments ?
A: You can send our your Purchase order ( if your company has ), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.
Q: How do you treat quality complaint ?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.
High Purity Pharmaceutical Intermediate Raw Material Fasudil Powder CAS 103745-39-7 Fasudil
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