Customization: | Available |
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Powder: | Yes |
Customized: | Customized |
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Product Name | Best Price Pharmaceutical Intermediate Anticancer Raw Abt-199 Venetoclax Powder CAS 1257044-40-8 Venetoclax |
Appearance | white powder |
CAS | 1257044-40-8 |
Assay | 99% |
Keywords | Venetoclax Intermediate;Venetoclax Powder;Raw Powder Venetoclax |
Shelf Life | 24 months when properly stored |
Storage | Keep in a cool, dry, dark location |
What is Venetoclax ? ABT-199 is a white powder, Venetoclax, also known as ABT-199 or GDC0199, ABT-199 is an orally bioavailable, selective small molecule inhibitor of the anti-apoptotic protein Bcl-2, with potential antineoplastic activity. ABT-199 mimics BH3-only proteins, the native ligands of Bcl-2 and apoptosis activators, by binding to the hydrophobic groove of Bcl-2 proteins thereby repressing Bcl-2 activity and restoring apoptotic processes in tumor cells. |
ABT-199 is a small molecule oral drug that treats chronic lymphocytic leukemia (CLL) in those with a specific chromosomal abnormality.In 2015, the United States Food and Drug Administration (FDA) granted Breakthrough Therapy Designation to venetoclax for subjects with CLL who have relapsed or have been refractory to previous treatment and have the 17p deletion genetic mutation.
Application of Venetoclax
Q: What's your MOQ ?
A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.