Factory Supply Pharmaceutical Raw Material Mitomycin C Powder CAS 51333-22-3 Bulk Mitomycin
| Product Name |
Factory Supply Pharmaceutical Raw Material Mitomycin C Powder CAS 51333-22-3 Bulk Mitomycin |
| Appearance |
Blue powder |
| Molecular formula |
C25H34O6 |
| Molecular Weight |
430.53 |
| Keywords |
Mitomycin Raw Material;Mitomycin C;Mitomycin C Powder |
| Shelf Life |
24 months when properly stored |
| Storage |
Keep in a cool, dry, dark location |
 |
What is mitomycin?
Mitomycin C is extracted from Streptomyces bacteria (bacteria) out of a broad-spectrum antitumor antibiotics, genetic toxicity and tumor resistance, is widely recognized inhibitors of DNA damage, have anti-cancer effect to many kinds of cancer, after activation, can play a role of DNA alkylating agent, action principle is to make the cell's DNA depolymerization, selective inhibit DNA, RNA and protein synthesis, cell and inhibiting tumor cell division.
This product is a non-specific drug in cell cycle. Its anti-tumor spectrum is wide and its effect is rapid, but the therapeutic index is not high. It is clinically applicable to cancers of digestive tract, such as gastric cancer, colorectal cancer, liver cancer and pancreatic cancer. It is also effective for lung cancer, breast cancer, cervical cancer and chorionic epithelial carcinoma. It can also be used for malignant lymphoma and malignant pleural effusion. |
Function of mitomycin
Mitomycin C (MMC), an antineoplastic antibiotic derived from Streptomyces caespitosus or Streptomyces lavendulae, is a cell cycle-specific alkylating agent, inhibits DNA synthesis through covalent mitomycin C-DNA adduct with EC50 values of 0.14μM in PC3 cells. Therefore, it was served as a chemotherapeutic agent that has demonstrated its antitumor activity and has been used widely in treatment of various cancers.
Although it is active against a wide variety of tumors, newer agents have largely replaced MMC except in anal cancer; outside of the United States, MMC is infrequently used for treatment of advanced non-small cell lung cancer (NSCLC), and breast cancer.
Application of mitomycin
(1) It is a cell division inhibitors, nucleic acid inhibitors and phage inducer; an anti-tumor drugs in clinical use.
(2) This drug has a broad anti-tumor spectrum, and effective for gastric cancer, breast cancer. It has a certain effect on lung cancer, liver cancer, malignant lymphoma, Hodgkin's disease, reticular cell sarcoma, uterine cancer, leukemia, intestinal cancer and pancreatic cancer, but with a short remission. Combination with urokinase can improve the efficacy. The goods exert its function quickly, but the number of operators is not high, and it has a high toxicity. The goods and bleomycin as well as its derivatives --doxorubicin are anti-cancer drugs of antibiotic which can disrupt DNA. It can depolymerize DNA in the cell, inhibit DNA replication in proliferating cell. The LD50 of intravenous injection of mice is 5ml It acts as an anticancer drugs, commonly used in the treatment of digestive system cancers.
Pharmaceutical Factory Supply API Mitomycin C CAS 51333-22-3 bulk Mitomycin powder
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Q: What's your MOQ ?
A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.
Q: Is there a discount ?
A: Yes, for larger quantity, we always support with better price.
Q: How to confirm the Product Quality before placing orders ?
A: You can get free samples for some proucts, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.
Q: How to start orders or make payments ?
A: You can send our your Purchase order ( if your company has ), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.
Q: How do you treat quality complaint ?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.
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